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Type 1 diabetics taking statins 7-12 years 5-times more likely to have cognitive impairment
Monday, July 17, 2017 7:00 pm Email this article
Type 1 diabetics taking statins for 7-12 years were 4.8 times more likely to have cognitive impairment compared to Type 1 diabetics who had never taking statins.
“Statin use was associated with cognitive impairment, particularly affecting memory, in these middle-aged adults with childhood-onset [type 1 diabetes], whom at this age, should not yet manifest age-related memory deficits,” the authors of the paper concluded.
They also note:
“Animal and cell culture studies show that statins can damage cerebral gray and white matter, thereby affecting cognitive function. Findings from human studies remain controversial; early observational studies reported that statin use negatively affected cognition, especially memory, while more recent studies have not replicated these findings.”
Of the 108 participants, 57 reported using statins, while 51 reported never using statins.
Nunley KA, Orchard TJ, Ryan CM, Miller R, Costacou T, and Rosano C. Statin use and cognitive function in middle-aged adults with type 1 diabetes. World J Diabetes, 2017 Jun 15; 8(6): 286-296.
Author’s Contact Info
Karen A Nunley, PhD, MS
Visiting Assistant Research Professor
Department of Epidemiology
University of Pittsburgh
5138 South Parran Hall
130 N De Soto St.
Pittsburgh, PA 15213, United States
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