Xenical causes weight loss of 4.7% in women with Polycystic Ovarian Syndrome (PCOS)

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Tuesday, November 23, 2004 12:39 pm Email this article
Xenical (orlistat) causes a weight loss of 4.7 percent in women with Polycystic Ovarian Syndrome compared to a weight loss of 1 percent for women given Glucophage (metformin). Subjects: Average of 27-years-old and BMI of 36.7

On average the women were 27-years-old and had a body mass index (BMI) of 36.7.

Both drugs reduced total testosterone

Both drugs reduced total testosterone.

Xenical (orlistat) reduced it from 115 ng/dl to 94 ng/dl, and metformin reduced it from 120 ng/dl to 97 ng/dl.

REFERENCE

Jayagopal V, Kilpatrick E, Holding S, Jennings P, Atkin S. Orlistat is as beneficial as metformin in the treatment of polycystic ovarian syndrome. J Clin Endocrinol Metab. 2004 Nov 9.

AUTHOR’S CORRESPONDENCE

V. Jayagopal
Department of Medicine
University of Hull
Michael White Centre for Diabetes and Endocrinology
Hull Royal Infirmary
Hull, UK, HU3 2RW

Department of Clinical Biochemistry and Immunology
Hull Royal Infirmary
Hull UK, HU3 2JZ

Department of Medicine
York Hospital
York, UK, YO31 8HE

Articles on the same subject can be found here:

• Polycystic Ovarian Syndrome

• Xenical (orlistat)