All-cause mortality over one-year was 16% higher (after adjustments) in people over 65 taking a tricyclic antidepressant compared to when patients were not taking an antidepressant according to a 2011 study from the U.K.
The absolute death rate was 8.12% over one year in those taking a tricyclic antidepressant compared to 7.04% for those not taking an antidepressant.
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