Extended-release niacin (1500 to 2000 mg per day) lowers levels of Lp(a) by an average of 28% in people starting with higher levels of Lp(a)—starting levels of 92 mg/dL versus 54 mg/dL—according to a study from Russia.
Elevated levels of Lp(a) (above 50 mg/dL) are associated with an increased risk of heart attack and stroke according to the Lipoprotein a Foundation.
Note: I prefer immediate-release niacin to extended-release niacin. In the 1980’s there were reports of some liver problems with extended-release niacin, and earlier studies showing benefits of niacin used immediate-release niacin, not extended-release.
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