Reanalysis of an old study, the Minnesota Coronary Experiment (MCE; 1968-73) which replaced saturated fat with vegetable oil rich in linoleic acid (an omega-6 polyunsaturated fat) from corn oil and corn oil polyunsaturated margarine, found NO benefit in reducing all-cause mortality—actually there was a 7% GREATER risk of death in the vegetable oil group, but the difference was not statistically significant—and NO benefit in reducing coronary heart disease mortality—actually there was a 13% GREATER risk of death from coronary heart disease in the vegetable oil group, but the difference was not statistically significant.
They also found that for every 30 mg/dL reduction in cholesterol levels in people 65 and older at baseline was associated with a 35% GREATER risk of death during the study.
“Paradoxically, MCE participants who had greater reductions in serum cholesterol had a higher, rather than lower, risk of death,” the paper notes.
The analysis was done by researchers at the US National Institutes of Health.
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